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The 29 Best Isekai Anime With OP Mc To Watch

isekai anime with overpowered main character

If you are a fan of isekai anime with an overpowered main character (OP MC)! then, you’re in luck! In this article, we’ll be showcasing the top 29 best isekai anime with an OP MC that you should add to your watchlist.

After a long and tiring day, there’s nothing better than unwinding with a good anime series. And if you’re someone who loves to immerse themselves in a different fantasy world, isekai-themed animes with OP MCs are a perfect choice. These shows allow you to escape from reality and witness a powerful MC doing their best to survive in a completely different realm.

So, whether you’re new to the isekai genre or a seasoned fan, we’ve got you covered with this list of the best other-world anime TV shows featuring an OP MC. Let’s dive in!

29. Marchen Awakens Romance

isekai anime with op mc

Kicking off the list of the top amazing isekai anime with an OP MC, with “Marchen Awakens Romance”, which is a series that should definitely be on your list. The story follows the protagonist Toramizu Ginta, who dreams of a magical world every night and yearns to go there. Despite receiving slander from others over his dreams, only his friend Koyuki believes in him.

One day, Ginta’s wish is granted when a large door appears before him, summoning him to the world of MAR. In this land, powerful weapons called ARMS exist. At first, Ginta is overjoyed to have finally discovered the magical world he had always dreamed of. However, he soon learns about the terrible wars that have ravaged MAR in the past and the upcoming war that threatens to tear it apart once again.

28. Isekai Cheat Magician

best isekai anime with op mc

Isekai Cheat Magician is an anime that perfectly fits the isekai genre with an overpowered main character. Nishimura Taichi and Azuma Rin, two high school students, are transported to a fantasy world full of monsters and mythical creatures. They decide to become adventurers, but little do they know that they possess cheat-level magic. With their powerful abilities, they quickly rise in the ranks and become a force to be reckoned with. Isekai Cheat Magician, with its stunning animation by Encourage Films, will take you on an adventure you won’t forget. Watch as Taichi and Rin use their overpowered magic to defeat anything that stands in their way.

27. Welcome to Demon School! Iruma-kun

isekai anime with op mc

Welcome to Demon School Iruma-kun is another great isekai anime with an OverPowered Main Character. The story follows the adventures of fourteen-year-old Iruma Suzuki, who has been unfortunate all his life, having to work to earn money for his irresponsible parents despite being underage.

One day, Iruma discovers that his parents have sold him to the demon Sullivan. At first, he is worried about what his future holds, but his concerns are soon alleviated when he realizes that Sullivan only wants a grandchild to dote on. Sullivan sends Iruma to attend the demon school, where he embarks on a new journey and discovers his hidden talents.

26. Seirei Gensouki

top adventure anime

Produced by TMS Entertainment, Seirei Gensouki: Spirit Chronicles is an incredible 2021 isekai anime with an op protagonist that you should really watch. The story is featuring Haruto Amakawa, a college student from Tokyo who dies in an accident and wakes up in a new world as a young boy named Rio. Haruto’s thoughts and memories merge with those of Rio, granting him magical abilities.

Rio is a boy who grew up in the slums and desires revenge for his mother’s murder, which he witnessed as a child. When he and Haruto rescue a kidnapped princess, the king rewards them by offering Rio a chance to study at a prestigious academy. Excited about this new opportunity, Rio believes it will be a turning point in his life. However, he soon realizes that life at the academy, surrounded by nobles and the upper class, is far from easy, and he struggles to fit in.

25. Shinchou Yuusha

another world animes

Also known in English as “Cautious Hero”, Shinshou Yuusha is a 2019 anime that spans multiple genres, including action, adventure, comedy, and isekai, and features an OP MC. Produced by White Fox studio, the story follows Seiya Ryuuguuin, who is summoned by the goddess Ristarte to save the world of Gaeabrande from destruction. Despite having overpowered stats, Seiya spends a considerable amount of time training and preparing for his noble journey. He fights even weak enemies using his strongest skills and stockpiles supplies and potions, prioritizing safety above all else.

Although Seiya’s approach may seem excessive or even annoying, it could be the key to saving Gaeabrande, a world where evil forces dominate every expectation. After all, it’s always better to be prepared for the worst, especially in a world where danger lurks at every turn.

24. Hataage! Kemono Michi

another world animes

Next up, we have Hataage! Kemono Michi, a hilarious isekai anime featuring a strong protagonist: professional wrestler Genzou Shibata. While his imposing physique and wrestling skills make him a formidable opponent in the ring, Genzou is also a huge animal lover at heart.

One day, during a title match against his rival, Genzou is abruptly transported to a fantasy world by a distressed princess seeking his aid in defeating a monster invasion. However, rather than accepting her plea, he takes her down with a powerful German suplex and escapes the castle. Stranded in this new realm, Genzou embarks on a new career as a beast hunter, determined to capture and befriend all sorts of creatures.

He is accompanied on his journey by Shigure, a wolf-girl, Hanako, a dragon-girl, and Carmilla Vanstein, a vampire, as they take on various dangerous quests to achieve Genzou’s ultimate dream of opening a pet shop.

23. The 8th son? Are you kidding me?

the 8th son

The 8th Son? Are You Kidding Me?” is a 2020 isekai anime that blends action and fantasy with themes of reincarnation and the growth of an op mc. The show follows the story of Shingo Ichinomiya, a 25-year-old salaryman who suddenly finds himself waking up in the body of a six-year-old boy named Wendelin Von Benno Baumeister in a parallel world. Despite his initial shock, Shingo quickly realizes that Wendelin possesses a remarkable gift: great magical aptitude. With this newfound power and his memories of his previous life, Shingo sets out to change his fate and rise from the ranks of a poor noble family to become a respected and wealthy member of society.


isekai anime with op mc

After a plane crash, seven talented Japanese high schoolers find themselves transported to the medieval fantasy world of Freyjagard, inhabited by two races: the animalistic byuma and the magic-attuned hyuma. Rescued by Winona and her elven daughter Lyrule, the group vows to repay their hospitality and find a way home using their skills and knowledge.

Under the guidance of Tsukasa Mikogami, Japan’s prime minister and their leader, they intervene in Freyjagard, gathering resources and learning about the culture. They suspect a connection between their situation and an ancient legend of seven heroes who defeated an evil dragon. But Tsukasa cautions them to take it slow and not disrupt this world with their advanced abilities.

21. Do You Love Your Mom and Her Two-Hit Multi-Target Attacks?

isekai anime with overpowered main character

Do You Love Your Mom and Her Two-Hit Multi-Target Attacks? is a light novel-based isekai anime with a unique twist: the main character is a female, Masato’s overpowered mother, Mamako. Masato and Mamako are thrown into a fantasy MMORPG world after completing a survey, much to Masato’s chagrin. Mamako is an expert swordsman with the power of two-hit multi-target attacks, and the two embark on a journey to clear the game. Along the way, they meet two other players, the merchant Porta, and the sage Wise, and form a party. The series is a mix of adventure, comedy, fantasy, and ecchi genres, and is produced by J.C. Staff.

20. Death March to the Parallel World Rhapsody

death march to the parallel world

Death March to the Parallel World Rhapsody is an isekai anime that follows an op mc named Satou, a programmer who unexpectedly finds himself in another world after taking a nap. He is surprised to find that he is at a beginner level, but he soon discovers that he possesses powerful abilities that he acquired before his arrival. In a desperate attempt to survive an encounter with a group of lizardmen, Satou uses his “Meteor Shower” ability, causing him to jump to level 310 and become extremely wealthy. With a new lease on life in this parallel world, Satou embarks on an adventure that blurs the line between reality and fantasy.

19. Black Summoner

isekai anime with op mc

Kuro no Shoukanshi, also known as Black Summoner, is a thrilling isekai anime released in the summer of 2022, produced by Satelight. The story follows Kelvin, a powerful Summoner who wakes up in a new world with no memory of his past life. Kelvin quickly discovers that he bartered away his memories for his summoning abilities, which he uses to fight formidable foes and embark on thrilling adventures. With his first follower being the very goddess who brought him to this new world, Kelvin develops a hidden disposition as a battle junkie and revels in each fight against his enemies. The epic saga of this overpowered adventurer and his allies is a must-watch for fans of action-packed isekai anime. 

18. Skeleton Knight in Another World

isekai anime with overpowered main character

Here is Skeleton Knight in Another World, which is a good choice among the top another world anime with an overpowered main character. In the virtual world of an MMO, Arc was just a regular player. But when he wakes up in a new world, he’s now the Skeleton Knight, a suit of armor inhabited by a skeleton. With his unique appearance, Arc must hide his true identity to avoid being attacked by others. He decides to become a mercenary and wander the land, keeping a low profile. However, when he witnesses injustice, he can’t help but intervene, using his strength and power to fight evil. This is the tale of a reluctant hero in an unfamiliar world, as he unintentionally becomes a force for good, one battle at a time.

17. Maou-Sama, Retry!

anime maou sama

Coming in, we have Maou Sama Retry, a great isekai anime with an op mc named Akira Oono who runs a popular MMORPG game called Infinity Game. One day, he decides to shut down the servers for good after fifteen years of managing the game. But at the stroke of midnight, something strange happens – he suddenly finds himself in the body of a middle-aged man named Hakuto Kunai, who happens to be the Demon Lord of Infinity Game!

As he tries to figure out how he ended up in this world, he comes across a young girl named Aku who is being chased by a demon named Greole. Despite not remembering anything about creating Aku or Greole, Hakuto is able to defeat the demon with ease. With Aku as his guide, he sets out to uncover the truth about his situation and discover who or what brought him to this fantasy world. However, his journey is not without consequences, as his powerful abilities cause destruction and chaos wherever he goes.

16. Uncle From Another World

uncle from another world

Uncle From Another World is a unique 2022 isekai anime with a powerful lead character, the series follows Takafumi, who is shocked to discover that his uncle has returned from a 17-year coma with an intense passion for video games. Even more surprising is the fact that his uncle had been transported to a fantasy world during his comatose state and emerged as a hero. As Takafumi tries to acclimate his uncle to the modern world, he also has to help him understand the evolution of gaming technology and pop culture. Can they bridge the two worlds and find a new path forward?

15. Farming Life in Another World!

farming life in another world

Ensuing, this is an isekai anime with op mc of 2023 where you can discover a whole new world of agriculture and adventure – Farming Life in Another World! Follow the story of Hiraku, a man who, after succumbing to a serious illness, is granted a second chance at life by God. But this time, he is transported to a mystical land of his choosing and gifted with a powerful farming tool that allows him to till the land with ease. Join Hiraku as he embarks on a journey of self-discovery and peaceful farming, creating a new life for himself in a world of endless possibilities.

14. In Another World With My Smartphone

In Another World With My Smartphone

This is the story of a man meets, who an untimely end due to an unknown error, only to be reborn in a parallel universe with a peculiar gift – a functioning smartphone. In this strange new world, he makes friends and learns about the secrets that lie within. Along the way, he discovers that he has inherited the knowledge of an ancient civilization and journeys through the laid-back kingdoms with their monarchs. Through his carefree travels, he explores the wonders of this new world and the limitless possibilities his smartphone provides him.

13. I’ve Been Killing Slimes for 300 Years and Maxed Out My Level

new isekai anime 2021

In I’ve Been Killing Slimes for 300 Years and Maxed Out My Level, the main character dies from overwork in the real world and is reincarnated as an immortal witch in another world. For 300 years, she enjoys a peaceful life, killing slimes to earn money and paying her bills. Due to her constant grind, she eventually reaches level 99 and becomes known as the strongest in the world. Her reputation attracts curious adventurers, dueling dragons, and even a monster girl who sees her as a mother figure. The witch, however, is not interested in fighting and prefers to keep her peaceful life. Nevertheless, she soon finds herself caught up in various adventures.

12. How NOT to Summon a Demon Lord

How NOT to Summon a Demon Lord

This is a refreshing isekai manga and anime series featuring an overpowered MC, that revolves around Diablo, who is considered the strongest player in Cross Reverie, making him a force to be reckoned with. With access to some of the game’s rarest and most powerful artifacts, even the most skilled players struggle to defeat him.

Unexpectedly, the main character Takuma is transported and reincarnated in the same game world. All he desires is to return back to Earth, and he’s aided in his quest by two girls who summoned and bound him with a contract. As Takuma explores this new world as an overpowered master of black magic, he becomes more confident and adept in his new life.

11. Hai To Gensou no Grimgar

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Well, the isekai anime with an op mc Hai to Gensou No Grimgar is a must-watch! The show follows the story of a group of teenagers who find themselves waking up in a strange world with no memory of their past, except for their names. They speak words that they have never heard before, yet the words feel familiar to them.

The group is recruited by the Reserve Army to protect the town from monsters that pose a threat to its safety. They must learn to fight these monsters in order to earn a living. After leaving the Reserve Army, Haruhiro, Manato, Ranta, Mogzo, and Shihoru must find a way to survive on their own, even though they are unable to defeat the weakest monsters. Their journey is filled with challenges as they try to navigate this unfamiliar world and uncover the mysteries of their past.

10. Tsukimichi: Moonlit Fantasy

Isekai anime with op mc

Tsukimichi: Moonlit Fantasy is an isekai anime featuring an overpowered main character named Makoto Misumi, who is summoned to an alternate world as a brave warrior. However, the goddess of the world finds his appearance ugly, strips him of his title, and banishes him to the wilderness. While there, he encounters various non-human species and develops extraordinary powers in magic and combat due to the differences in the environment from his home world. Makoto must survive in this new world while dealing with various encounters and working toward social reform.

9. The Eminence in Shadow

the eminence in shadow

The Eminence in Shadow is a 2022 isekai anime with an op mc. Cid dreams of becoming a Shadowbroker, an invisible puppet master controlling everything behind the scenes. But a fatal traffic accident prevents him from fulfilling his aspirations. However, he wakes up in a new world, where he leads a secret organization fighting against evil. With this new opportunity, Cid can finally act out his delusional fantasies and become the mastermind he always wanted to be.

8. Arifureta: From Commonplace to World’s Strongest


Arifureta is a popular isekai anime with an overpowered main character named Hajime Nagumo. The story follows the ordinary life of a 17-year-old otaku, Hajime, whose life is turned upside down when he and his classmates are summoned to a fantasy world to save mankind.

However, Hajime’s life takes a dark turn when he is belittled by his classmates for only gaining an inferior power that lacks any real offensive capabilities. Even with this setback, Hajime resolves to survive and become stronger, delving deep into dangerous dungeons and fighting powerful monsters to gain experience and strength.

Through his trials, Hajime gains powerful abilities and weapons that make him one of the most formidable fighters in this another world. With his newfound strength and determination, Hajime sets out on a quest for revenge against those who wronged him, determined to become the strongest hero in the world.

7. Kenja no Mago

isekai anime with overpowered main character

Kenja No Mago is a pretty good isekai anime that follows the story of Shin, an orphan who is reincarnated into an outer fantasy kingdom where he is raised by the legendary hero of the kingdom, Merlin Walford, in the solitude of the forest. Shin displays an incredible affinity for magic, and on his 15th birthday, he is sent to the kingdom’s Magic Academy to further train and develop his social skills, in addition to his magical abilities. As he continues to hone his skills, Shin becomes an incredibly powerful and formidable character, earning the title of an op badass.

6. Tate no Yuusha no Nariagari

isekai anime with overpowered mc

Also known in English as “The Rising of the Shield Hero”, this is an isekai show that follows the underestimated main character Naofumi, who experiences a great betrayal from someone he considered a friend, causing his reputation to plummet. Throughout his journey in this other world, the main character becomes overpowered and works to rebuild his image, ultimately seeking revenge against those who wronged him. This is a well-recommended anime series, which debuted in January 2019 and consists of 25 episodes filled with action, drama, and a dark storyline following the development of an Op Mc seeking redemption and justice.

5. Youjo Senki


Up next is Youjo Senki, an isekai anime with a strong main character that takes a different twist on the typical fantasy world filled with magical powers and mythical creatures. Instead, the main character finds himself reincarnated as a yandere little girl in a war-torn world. Tanya is her name, and she is determined to rise through the military ranks and achieve victory in battle, even if it means becoming part of a rapidly growing empire. As Tanya fights on the frontlines, her ruthless tactics and unwavering ambition may make her enemies, but she is determined to emerge victorious.

4. Log Horizon

loh horizon 3rd season

Continuing our list with this fantastic isekai anime, “Log Horizon,” which features an incredibly powerful main character. The story centers around Elder Tale, an online RPG that allows players to embark on thrilling adventures in various worlds. Unfortunately, when the twelfth expansion pack, “Novasphere Pioneers,” glitches, 30,000 Japanese players become trapped inside the game.

One of these players is Shiroe, a shy grad student who struggles to communicate with others. In order to survive in this perilous new world filled with monsters, Shiroe forms a guild called “Log Horizon” with a diverse group of fellow players. Together, they must navigate through the challenges of this game world and find a way to escape back to reality.

3. Overlord

another world anime

Overlord is among the best isekai anime series with an op mc of all time. The series follows Momonga, who decides to log out as the game’s servers (Yggdrasil, a popular online game) shut down. However, he finds himself trapped in the game world of Yggdrasil, now transformed into a powerful skeletal wizard.

As time passes, the game world begins to change, with NPCs becoming increasingly lifelike and emotional. Momonga, who has had his emotions suppressed, becomes cold and calculating and sets out to take over the new world of the game. With no family, friends, or place in society, this ordinary young man becomes determined to rule this new reality.

3. That Time I Got Reincarnated as a Slime

reincarnated as a slime

First seen in 2018, That Time I Got Reincarnated as a Slime is an isekai anime with an op mc, Satoru Mikami is a lonely, dissatisfied 37-year-old stuck in a dead-end job. After dying at the hands of a robber, he awakens to a fresh start in a fantasy realm as a powerful slime monster. As he adjusts to his new goopy existence, his interactions with other monsters lead to a series of events that will transform his new world forever.

2. No Game No Life

no game no life

At number 2 we have No Game, No Life, a captivating isekai anime that blends action, gaming, and adventure genres. The story revolves around the protagonist duo, Sora and Shiro, who are reclusive professional gamers, devoting their time to playing video games.

These two expert gamers have conquered all their favorite games, and they even believe that the “real world” is just another “lame game.” However, their lives take an unexpected turn when they are summoned by a mysterious boy to an alternate universe.

The boy is the master of this new world, where games determine everything, even the fate of nations. He has put an end to wars, and humanity has been pushed into a single city, oppressed by other races.

1. Mondaiji Tachi

isekai anime with op mc

Our list of the best isekai anime with overpowered main characters comes to an end with the inclusion of Mondaiji Tachi, an incredible otherworld anime. The story follows three main characters, Izayoi Sakamaki, Asuka Kudou, and You Kasugabe, who are all bored with their mundane lives.

However, their lives take an exciting turn when they receive an envelope each and upon opening them, they are transported to a new reality. In this new world, they are tasked by The Black Rabbit to help overthrow the Devil King. Mondaiji Tachi is such an amazing addition to any isekai anime with an op mc fan’s watch list.

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