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The 20 Best isekai Anime of 2022 to Watch Right Now

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The following article lists the top and the best new Isekai Anime of 2022 To Watch.

With the rapid rise of so many good anime series, chances are high that the isekai anime 2022 releases will be spectacular.

Isekai anime is one of the most popular genres in the industry. It has been around for a while and it is not going anywhere anytime soon. In this article, we will be listing the best isekai anime to watch. We will also be looking at some of the most appreciated isekai anime series released in 2022.

Why You Should Be Watching Isekai Anime

Isekai anime is a genre of anime that features characters who are transported to alternate universes. The word “isekai” means “another world” in Japanese. These stories typically involve the protagonist being transported to a world with strange customs and/or different technology levels than the world they came from.

Some of these stories are set in a medieval-style fantasy world, while others take place in more technologically advanced worlds. It can be difficult for an outsider to understand the customs and culture found in these worlds, which is what makes them so interesting to watch!

With no further addition, here are the best new isekai anime set in an alternate reality from the year 2022 that every fan should watch!

20. Uncle From Another World

Uncle From Another World

Can’t say that I’ve seen many quality isekai anime tv shows like this lately. This show has a different concept to it, revolving around Uncle and Nephew. Yōsuke Shibazaki (Uncle) and Takafumi Takaoka (Nephew) are the two main characters in this another world anime series.

Seventeen years ago, Takafumi’s uncle fell into a coma but now he’s back like a man been risen from the grave.

Right after that, Takafumi finds out two surprising mysteries: His uncle used to be a vivid gamer and during his coma, he was also teleported to another world!

Now Takafumi, rooming with his uncle who was utterly ignorant about advances in the past two decades, like high-speed internet, technologies, and modern anime. Now he has to catch up with him on what happened when he was comatose.

19. Isekai Yakkyoku

good isekai anime 2022

After working himself to death at the age of 31, the former pharmacist discovers that he has been reincarnated into a medieval world as Falma, a child of the respected De Médicis family.

In such a magical world, It turns out that Falma’s body is actually a host of the guardian deity of medicine. The boy has been granted magical abilities as well as the ability to diagnose illnesses in people with a quick touch.

He soon discovers that medical care is a privilege that only nobles get to experience in this universe. Even though, it can be ineffective or even detrimental.

Using his modern knowledge and divine power, Falma has always wanted to improve the healthcare situation in the San Fleuve Empire and make it easier for everyone to access. With his pharmacy skills, he’ll get closer to his goal.

18. Reincarnated As A Sword

Reincarnated As A Sword

This is another good isekai anime of 2022 that you will absolutely fall in love with.

Chased, tortured, and killed – this is the tragic story of what happens to the Black Cats tribe.

Fran is a young girl who is a Black Cats Tribe member, she has been oppressed and persecuted since birth. Growing up in a dark world, she’s always dreamed of being able to get her revenge against those who have done wrong to her people.

She will cross paths with a talking sword looking for a beautiful wielder. The encounter changes the course of her life. With the help of her new cunning ally, Fran will fight to get the recognition of belonging and recognition that has been denied to her kinfolk. With an unyielding force, she embarks on a treacherous journey with her magical sword.

17. In the Land of Leadale

best isekai anime 2022

This new isekai series follows Keina Kagami, a young woman who gets transported into the VRMMORPG world of Leadale after the life support that kept her alive fails. Reincarnated in the body of her old character, “Cayna,” she immediately notices that things are different from what she remembers. She learns that 2 hundred years have passed since she last played.

However, Cayna is not disappointed by this. As a new isekai journey awaits with unfamiliar faces and many exciting prospects to be discovered. In The Land of Leadale has streamed during the winter of 2022, has 12 episodes and its genres span adventure, fantasy, isekai, and reincarnation.

16. Ascendance of a Bookworm Season 3

isekai anime of 2022

Isekai series like Ascendance of a Bookworm are popular with people because they’re still valid and exciting. It’s a good thing that we got the chance once again to watch the third season in April 2022.

The story of the reincarnated book-lover Myne straddles between two worlds. In a past life, she died in an earthquake that took place as she was saving books from the collapsing stacks. Instead of dying in real life forever and disappearing into a void, she wakes up in the new body of Myne in another world where she has to complete the mission. All her missions give her a chance to help books reach more people in this world.

15. Black Summoner

black summoner

Black Summoner is a good 2022 isekai anime series that follows the story of Kelvin, who wakes up in an unknown new place with no memories of his previous life. He learns that he’s bartered away those memories for powerful abilities.

Kelvin had just become a Summoner, and his first Follower was the very girl who had brought him to this world. Kelvin had begun his exciting new life as an adventurer. And it wasn’t long before he discovered one of his hidden personality traits… His love for combat!

The anime has an exciting story about one overpowered hero, who fights against incredible evil forces. Join this intrepid character as he sets off on one thrilling and perilous adventure after another, with help from friends to mark their names into history.

14. How a Realist Hero Rebuilt the Kingdom Season 2

How a Realist Hero Rebuilt the Kingdom Season 2

The release date of Realist Hero Part 2 was during the Winter 2022 anime season. This means that it’s a split run, which is when a single season takes a break before continuing.

This is a pretty good isekai anime sequel of 2022 that takes place in another world, where Kazuya Souma becomes the new king after being summoned.

As a realist, he creates a revolutionary system of government administration based on intellectual skills. This is a fantasy world where dragons, monsters, and elves exist, as well as some other interspecies

13. The Greatest Demon Lord Is Reborn as a Typical Nobody

best isekai anime in 2022

Some people say this anime isn’t an isekai, but I think we’re watching a good isekai tv show here as it tackles a lot of the same themes.

This is one of the best isekai anime of 2022, with an epic story of the Demon Lord Varvatos, who had become bored with reigning as the strongest being in the world and wanted to go to a time where his abilities would compete with others. Unfortunately for him, when he got reincarnated thousands of years later, it seems like the people he used to know are in a period of tranquility and are now weaker than before.

Now he’s back to full power, ladies are fawning over him again and the royal family is begging him to be the next king. In addition, a servant wants him dead – ah, but even now that has not deterred his one-track mind from carrying out his ultimate goal of living a normal life.

12. Ouji no Honmei wa Akuyaku Reijou

2022 isekai anime

Well, in our next isekai series we’re talking about the opposite of someone being reincarnated as a hero. Normally she’s a villain in this show, but at the same time, she may seem actually the protagonist this time around. The first night of her reincarnation. He kisses her deeply and kisses every inch of her body… and gave her their first sweet kiss.

This is a unique isekai anime of 2022 that depicts a story about a hardworking girl who dies and is reincarnated as the villain in her favorite game but will she be able to keep her fiancé safe or will the protagonist take him away from her?

11. She Professed Herself Pupil of the Wise Man

isekai anime list

With his dignified appearance and long white beard, Summoner Mage Dunbalf was one of the strongest player characters in Ark Earth Online. He is also widely heralded as being a one-man army during battles. But one day Dunbalf and all the other Mages suddenly went missing. No trace was left behind.

Dunbalf has been trying to spend his expiring credits with every new purchase, but unfortunately fell asleep while trying to customize his character in the game. After waking up in Ark Earth Online, Dunbalf discovers that the game world has become more realistic and now he’s turned into a cute girl. He also sees that 30 years have passed, so he decides to investigate, find the other mages, and claim his legacy…

10. Tensei Kenja no Isekai Life: Dai Ni no Shokugyou wo Ete, Sekai Saikyou ni Narimashita

new isekai anime 2022

Known also as My Isekai Life: I Gained a Second Character Class and Became the Strongest Sage in the World, this is another good isekai anime 2022 to enjoy.

The anime spans genres of action, adventure, and fantasy, it is currently airing, and depicts the story of Yuuji Sano, a black company employee who just finished his work for the day, is suddenly summoned to another world. His profession in that other world, being a Monster Tamer, makes it impossible for him to become an adventurer.

However, after meeting some slimes that read many magical books, he gained some magical powers and became a sage. Yuuji suddenly became the strongest person in the world but is he fully conscious of his power?

9. The Eminence in the Shadow

The-Eminence-in-Shadow-Anime

The Eminence in the Shadow is an action, comedy, fantasy, isekai anime that will air in October 2022, the story follows Cid couldn’t live his dream of being the mastermind behind everything in his previous life, but now he has been reincarnated in a fantasy world and the question is whether he will be able to achieve his goal or not?

In this world, Cid is pretending to be just another average mob character, but really he’s trying to destroy the evil cult that lurks in the shadows. he starts recruiting a couple of members who want to join his (fake) organization Shadow Garden and his aim is to head out in hopes of taking down the cult.

8. Harem in The Labyrinth of Another World

isekai anime of 2022

Produced by Studio Passione and adapted from the Light Novel of the same name, Harem in The Labyrinth of Another World spans genres: action, adventure, fantasy, romance, ecchi, and harem.

It tells the story of Michio Kaga, Struggling with life and society, he ventures into the world of the internet and stumbles upon an unusual website. Upon entering, he is greeted by a series of questions and is given points based on his responses. Michio creates a character with skills and abilities based on his responses.

With his brand-new character, Kaga gets transported to a fantasy world and reborn as an overpowered man who could easily claim idol girls. The harem legend starts here!

7. Arifureta Season 2

new isekai anime series

Arifureta is among the best Japanese isekai anime series that premiered in 2019. The second season of the show aired in winter 2022.

The overpowered main character is a common subplot in the isekai genre, and Arifureta is one such good isekai anime with an op mc. Hajime Nagumo and his class are summoned to an alternate world of magic. Unlike their classmates, though, he’s not given any particularly powerful skills.

Betrayed by his classmates, Hajime has to fight to survive, eventually teaming up with various women who join him on his journey from being an average person in a mundane world, to the strongest in this another world.

6. The Executioner and Her Way of Life

new isekai anime tv shows 2022

This isekai anime 2022 follows the student Mutou Mitsuki, who suddenly finds himself transported to another world. He is summoned by the king of this world for possessing a power that he’s not even sure of and then he found out that he doesn’t actually have any power whatsoever.

Whinging to himself, he encountered a priestess named Menou who explained that Japanese people like him are known as Lost Ones and such people never fail to have special powers. Menou is actually from a church that helps Lost Ones mingle into society. She invites him to spend the night at her place, where they can investigate his mysterious ability. Finally, they figure out that he has overpowered yet dangerous powers.

Nevertheless, Menou hides her motives and ends up killing Mutou instantly. Because, after 4 incidents where Lost Ones caused major damage, the church has ordered that all foreigners be killed. Now that there are other Lost Ones, who were summoned by the king, Akari Tokitou, they must be eliminated and that task falls to Menou.

5. Trapped in a Dating Sim: The World of Otome Games Is Tough for Mobs

new isekai anime series 2022

Trapped in a Dating Sim: The World of Otome Games is Tough for Mobs, is a good 2022 Isekai anime that is worth checking out, since it unveils the truth about the gaming world.

This anime’s story revolves around Leon- he was a boring office worker in his previous life but is reborn into the world of dating sim video games. He’s living a brand new life as an in-game character and is ready to undergo such an epic adventure.

In this game world, he has to basically find out the shadowy people that trapped him there. With his backstory and the retained memories from his previous life, he will have an immense advantage in such a new life.

4. Life with an Ordinary Guy who Reincarnated into a Total Fantasy

another world anime 2022

Next up, we have another fresh and new isekai anime of 2022 that depicts: Since school, Tsukasa was lucky with women due to his good looks, but Tachibana has had very little. However, while Tsukasa has never shown interest in the opposite sex at all, Tachibana is always dreaming to have a girlfriend.

Even though they are complete opposites, these two have stayed best friends. One night, they were coming home from a party where Tsukasa was the center of attention as usual. Tachibana in a drunk state, he unwillingly wishes to be a girl, charming enough to steal anyone with eyes.

As if they had been answered by the heavens, someone appeared before them, transporting them to another world to defeat the Demon Lord and granting Tachibana’s deep desire. Tachibana found himself in the body of an impossibly attractive girl and he instantly attracted everyone. Even his friend succumbed to her charms.

Tachibana gets a glimpse of Tsukasa’s good looks and understands the reason for his popularity. Before they get caught up in each other forever, they need to complete their mission or else risk staying in their weird love story.

3. Skeleton Knight in Another World

Skeleton-Knight-In-Another-World

Much like the popular anime series Overlord, Skeleton in Another World is a good isekai anime recommendation that aired in the Spring of 2022.

This is the story of a vivid gamer who was playing video games until he fell asleep…and when he woke up, he found himself in the game world. As it turned out, his body had been replaced by a skeleton.

Featuring powerful weapons and armor with a frightening skeletal appearance, it doesn’t take long for our hero to realize that he has to find his place in this new land. However, all his dreams for a relaxing life are shattered when he meets a mysterious elven warrior, setting him on an adventure full of danger and excitement.

2. Overlord Season 4

overlord season 4

If you love isekai themed-anime, you might already watch Overlord, which is one of the most popular isekai anime of all time. Needless to say, this year’s fourth season was one of the most anticipated and received a lot of praise once it started airing in 2022.

Overlord follows the adventures of Momonga, a powerful wizard in a popular video game who still playing until the game’s servers are about to shut down. After the game shut down, he notices that he’s still conscious in the game, and he ponders if his guild mates are still logged on too.

When faced with this odd situation, Momonga commanded his servants to help him investigate and try to find out what has led to this development and if there are other people in the same condition.

1. The Rising of The Shield Hero Season 2

The Rising of The Shield Hero Season 2

The hype around Rising of the Shield Hero has been getting stronger for a long time now, mainly because it’s one of the most anticipated Isekai anime in 2022. If you’re looking for some good viewing this year, I would recommend picking up Season 2 of Rising of the Shield Hero as well.

This is is a top-rated isekai anime tv show that shares the story of a boy who’s betrayed, takes revenge, and comes out overpowered. It has been praised for being an innovative story with many twists.

Suddenly, The main character was transported to another world with a shield that made him one of the world’s best defenders. This adventure started off strong, but the protagonist had to completely start over when his reputation was shattered. The desire for revenge and regaining his good reputation is the driving factor of this story.

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